A Single Drop to Bigger, Brighter, More Beautiful Eyes
Upneeq is the only FDA-approved prescription eye drop for acquired ptosis (drooping eyelids), lifting the upper lids to open your eyes in as little as 10 minutes.
Upneeq is a daily prescription drop for acquired ptosis that gently raises the upper eyelids, creating a more open and refreshed look.
• 30 to 90 day supply. One dose, once daily
• See results in as little as 5-15 minutes
• Lasts up to 8 hours
• Significantly improves upper field of vision
• No more tired-looking or asymmetrical eyes
• Non-surgical alternative to blepharoplasty
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"Experience a refreshing lift with just one daily drop."
In one study, some patients saw a lift in their eyelids as fast as 5 minutes after the first dose
74% of patients had more than a 50% improvement
Most patients in clinical trials had a lift in their eyelids in as little as 2 hours
84% of patients had some form of improvement
Is Upneeq right for you?
Have you noticed your eyelids starting to droop? You might have acquired ptosis, also known as low-lying lids.
Acquired Ptosis (low-lying lids) is a common condition that:
Can develop later in life.
Affects adults of all ages, becoming more common as we get older.
Occurs when the muscles that lift the eyelid weaken or stretch, causing the upper eyelid to sag.
May be linked to factors like cataract surgery, long-term contact lens use, or certain medical conditions.
Could sometimes indicate a more serious health concern.
Can impact vision.
Low-lying lids can affect both your sight and appearance:
Blocking your upper field of vision.
Reducing your overall field of vision.
Making daily tasks—like reading, driving, using a computer, or looking up—more difficult.
They can also affect how you feel about your appearance:
Making you look tired even when you’re not
Creating uneven or asymmetrical eyes
Key Ingredients
UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution), 0.1% is a prescription eye drop used to treat acquired blepharoptosis (low-lying lids) in adults.
Contains oxymetazoline hydrochloride, an alpha adrenoceptor agonist. UPNEEQ® is an aseptically prepared, sterile, non-preserved ophthalmic solution. Each mL of UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution) 0.1% contains 1 mg of oxymetazoline hydrochloride, equivalent to 0.09 mg (0.09%) of oxymetazoline free base. The ophthalmic solution contains the following inactive ingredients: calcium chloride, hydrochloric acid (used to adjust pH to 5.8 to 6.8), hypromellose, magnesium chloride, potassium chloride, sodium acetate, sodium chloride, sodium citrate, and water for injection.
Upneeq should only be used as directed
- The solution should never be swallowed or ingested in any other way
- Upneeq should be stored at 68°F-77°F (20°C-25°C) and should be protected from excessive heat
- Keep out of reach of children
FAQs
What is UPNEEQ?
UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution), 0.1% is a prescription eyedrop used to treat acquired blepharoptosis (low-lying lids) in adults.
Does Insurance cover Upneeq?
No, Upneeq is considered an elective cosmetic treatment that is not covered by insurance.
What warnings and precautions are associated with UPNEEQ?
- Low-lying lids may be related to conditions such as stroke and/or brain aneurysm, Horner syndrome, myasthenia gravis, loss of the ability to move eye muscles, eye infection and eye tumors. Tell your doctor if you have any of these conditions.
- UPNEEQ is a type of medication that may affect your blood pressure. If you have heart disease, uncontrolled high or low blood pressure, or feel faint at rest or when quickly standing up, you should call your doctor if your symptoms get worse.
- Patients with reduced blood flow to the brain or heart, or patients who experience eye or mouth dryness due to an immune system disorder (Sjögren’s syndrome), should use care when taking UPNEEQ. Call your doctor immediately if you feel your symptoms may be getting worse.
- UPNEEQ may increase the risk of eye pressure due to fluid buildup (angle-closure glaucoma) in patients with untreated narrow-angle glaucoma. Call your doctor immediately if you feel increased pressure in your eye after using UPNEEQ.
- Do not let the tip of the UPNEEQ vial touch your eye or any other surface. This can help prevent eye injury or contamination. Each UPNEEQ vial is for one-time use and should be discarded after being used.
What are the most common side effects of UPNEEQ?
The most common adverse reactions with UPNEEQ (occurring in 1-5% of patients) were eye inflammation, eye redness, dry eye, blurred vision, eye pain at time of use, eye irritation, and headache.
What should my doctor know about before prescribing me UPNEEQ?
- Your doctor should review your full medical history before prescribing UPNEEQ.
- UPNEEQ belongs to a class of medication (alpha-adrenergic agonists) that may affect your blood pressure. Use UPNEEQ carefully if you currently take an alpha-adrenergic agonist medication to treat heart disease or an enlarged prostate. Patients taking beta-blockers, or other medications to treat hypertension or an abnormal heartbeat, should also be careful when using UPNEEQ.
- Patients who use a certain class of antidepressant medication (monoamine oxidase inhibitors) should also be careful when using UPNEEQ, as it may affect the way your body absorbs the medication.
How quickly does Upneeq work
It can work in as fast as 5 minutes with peak lift typically occurring by 2 hours.
How long does Upneeq last?
Just one drop of Upneeq can temporarily lift the upper lid for up to 8 hours.
How do I use Upneeq?
1. Cut open foil wrapper and remove single-use vial
2. Apply one drop to each affected eye as directed, once a day or on days when your eyelids need a lift
3. Discard the single-use vial after use
• Upneeq vials are single-use only and should not be reused after opening
• After applying the drops, immediately discard the vial in the trash
Can I use Upneeq if I wear contacts or if I use other kinds of eye drops?
• If you wear contact lenses, remove them before using Upneeq. You should wait at least 15 minutes before placing them back into your eyes
• If you are using Upneeq with other eye (ophthalmic) medicines, you should wait at least 15 minutes between using Upneeq and the other medicines. Contact your eyecare professional if you have additional questions
• View full Important Safety Information
Is Upneeq safe?
• In clinical trials, Upneeq was proven to be safe and effective when used as directed
• Common side effects (seen in 1-5% of patients) included eye inflammation, eye redness, dry eye, blurred vision, instillation site pain, eye irritation, and headache
• View full Important Safety Information
What should I be aware of before using Upneeq?
• Upneeq is a type of medication that may affect your blood pressure. If you have heart disease, uncontrolled high or low blood pressure, or feel faint at rest or when quickly standing up, you should call your doctor if your symptoms get worse.
• Patients with reduced blood flow to the brain or heart, or patients who experience eye or mouth dryness due to an immune system disorder (Sjögren’s syndrome), should use care when taking Upneeq. Call your doctor immediately if you feel your symptoms may be getting worse.
• Upneeq may increase the risk of eye pressure due to fluid buildup (angle-closure glaucoma) in patients with untreated narrow-angle glaucoma. Call your doctor immediately if you feel increased pressure in your eye after using Upneeq.
• View full Important Safety Information.
These are not all of the possible side effects of UPNEEQ. Tell your medical provider if you have any side effects that bother you or do not go away. Call your medical provider for medical advice regarding any side effects, or seek immediate medical attention if an emergency.
To report side effects or product complaints, contact RVL Pharmaceuticals at 1-877-482-3788. You may also report side effects to the FDA by calling 1-800-FDA-1088 or visit www.fda.gov/medwatch.
This is a summary of the most important safety information for UPNEEQ. For more in-depth safety information, please review the full Prescribing Information for UPNEEQ. https://www.upneeq.com
*LegitScript certification means that our practice has been carefully reviewed and approved as a trusted, compliant healthcare provider. It shows that we meet strict standards for safety, transparency, and responsible patient care. For you, this means greater confidence that you’re receiving services from a verified and reputable organization committed to high-quality, ethical treatment.
*Prescription treatment requires an online intake form, and photos uploaded of your face for a medical provider to determine if a prescription is appropriate. Actual product packaging may appear differently than shown.
*Upneeq is a registered trademark of RVL Pharmaceuticals, Inc. Restored Wellness is not affiliated with RVL Pharmaceuticals, Inc.
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